Ampicillin capsules are a broad-spectrum penicillin antibiotic used to treat infections caused by susceptible bacteria. Key applications include:

1. Respiratory Tract Infections

• Pneumonia, bronchitis, tonsillitis, pharyngitis, and sinusitis caused by Streptococcus pneumoniae, Haemophilus influenzae, or Staphylococcus aureus .

2. Urinary Tract Infections (UTIs)

• Cystitis, pyelonephritis, and gonococcal infections due to Escherichia coli, Proteus mirabilis, or Neisseria gonorrhoeae .

3. Skin and Soft Tissue Infections

• Cellulitis, abscesses, and wound infections caused by susceptible Gram-positive and Gram-negative bacteria .

4. Gastrointestinal Infections

• Typhoid fever, paratyphoid fever, and dysentery caused by Salmonella or Shigella species .

5. Central Nervous System Infections

• Bacterial meningitis and encephalitis (combined with aminoglycosides for enhanced efficacy) .

6. Cardiovascular Infections

• Endocarditis caused by Enterococcus faecalis or streptococci (often combined with gentamicin) .

7. Preventive Use

• Prophylaxis against group B streptococcal infections in newborns during labor .

Key Notes:

• Administered orally on an empty stomach (0.5–1 g every 4–6 hours) .

• Contraindicated in penicillin-allergic patients or those with severe renal/hepatic impairment .

• May interact with drugs like probenecid (increases serum levels) or oral contraceptives (reduces efficacy) .

For dosage adjustments in pregnancy, pediatrics, or special populations, consult a healthcare provider.